Topoisomerase II binds to ellipticine in the absence or presence of DNA. Characterization of enzyme-drug interactions by fluorescence spectroscopy.

Froelich-Ammon SJ, Patchan MW, Osheroff N, Thompson RB
J Biol Chem. 1995 270 (25): 14998-5004

PMID: 7797481 · DOI:10.1074/jbc.270.25.14998

MeSH Terms (14)

Base Sequence DNA DNA Damage DNA Topoisomerases, Type II Ellipticines Hydrogen-Ion Concentration Kinetics Models, Structural Molecular Sequence Data Oligodeoxyribonucleotides Protein Binding Recombinant Proteins Saccharomyces cerevisiae Spectrophotometry

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