Variable effects of maturity-onset-diabetes-of-youth (MODY)-associated glucokinase mutations on substrate interactions and stability of the enzyme.

Liang Y, Kesavan P, Wang LQ, Niswender K, Tanizawa Y, Permutt MA, Magnuson MA, Matschinsky FM
Biochem J. 1995 309 ( Pt 1): 167-73

PMID: 7619052 · PMCID: PMC1135815 · DOI:10.1042/bj3090167

MeSH Terms (19)

Adenosine Triphosphate Age of Onset Animals Base Sequence Diabetes Mellitus, Type 2 DNA Primers Enzyme Stability Glucokinase Glutathione Transferase Hexokinase Humans Islets of Langerhans Kinetics Molecular Sequence Data Mutation Rats Recombinant Fusion Proteins Saccharomyces cerevisiae Substrate Specificity

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