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Anti-transforming growth factor (TGF)-beta antibodies inhibit breast cancer cell tumorigenicity and increase mouse spleen natural killer cell activity. Implications for a possible role of tumor cell/host TGF-beta interactions in human breast cancer progression.

Arteaga CL, Hurd SD, Winnier AR, Johnson MD, Fendly BM, Forbes JT
J Clin Invest. 1993 92 (6): 2569-76

PMID: 7504687 · PMCID: PMC288452 · DOI:10.1172/JCI116871

MeSH Terms (22)

Animals Antibodies Breast Neoplasms Cell Division Collagen Cytotoxicity, Immunologic Factor VIII Female Humans Immunoglobulin G Killer Cells, Natural Lung Neoplasms Mice Mice, Nude Neoplasm Metastasis Neoplasm Transplantation Neovascularization, Pathologic Recombinant Proteins Spleen Transforming Growth Factor beta Transplantation, Heterologous Tumor Cells, Cultured

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