Increased drug affinity as the mechanistic basis for drug hypersensitivity of a mutant type II topoisomerase.

Froelich-Ammon SJ, Burden DA, Patchan MW, Elsea SH, Thompson RB, Osheroff N
J Biol Chem. 1995 270 (47): 28018-21

PMID: 7499285 · DOI:10.1074/jbc.270.47.28018

MeSH Terms (19)

Amino Acid Sequence Animals Base Sequence Binding, Competitive Chemokines Cloning, Molecular DNA Primers Humans Interleukin-8 Iodine Radioisotopes Kinetics Mice Molecular Sequence Data Polymerase Chain Reaction Receptors, Interleukin Receptors, Interleukin-8B Recombinant Fusion Proteins Recombinant Proteins Sequence Homology, Amino Acid

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