Stability of antimicrobial agents in peritoneal dialysate.

Sewell DL, Golper TA
Antimicrob Agents Chemother. 1982 21 (3): 528-9

PMID: 7103451 · PMCID: PMC181931 · DOI:10.1128/aac.21.3.528

The stability of cephapirin, gentamicin, penicillin G, nafcillin, ticarcillin, and vancomycin was tested in peritoneal dialysate at 25 degrees C for 24 h. All of the antimicrobial agents were stable except penicillin G, which lost 25% of activity over 24 h (P less than 0.01). The once-daily preparation of drug-dialysate solution is feasible for the treatment of peritonitis in patients on continuous ambulatory peritoneal dialysis.

MeSH Terms (3)

Anti-Bacterial Agents Drug Stability Peritoneal Dialysis

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