Estimating the likelihood of significant coronary artery disease.

Pryor DB, Harrell FE, Lee KL, Califf RM, Rosati RA
Am J Med. 1983 75 (5): 771-80

PMID: 6638047 · DOI:10.1016/0002-9343(83)90406-0

Among 23 clinical characteristics examined in 3,627 consecutive, symptomatic patients referred for cardiac catheterization between 1969 and 1979, nine were found to be important for estimating the likelihood a patient had significant coronary artery disease. A model using these characteristics accurately estimated the likelihood of disease when applied prospectively to 1,811 patients referred since 1979 and when used to estimate the prevalence of disease in subgroups reported in the literature. Since accurate estimates of the likelihood of significant disease that are based on clinical characteristics are reproducible, they should be used in interpreting the results of additional noninvasive tests and in quantitating the added diagnostic value.

MeSH Terms (18)

Adult Aged Angina Pectoris Coronary Disease Diabetes Complications Electrocardiography Female Humans Hyperlipidemias Male Mathematics Medical History Taking Middle Aged Models, Theoretical Myocardial Infarction Probability Risk Smoking

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