Drug prescribing in renal failure: dosing guidelines for adults.

Bennett WM, Aronoff GR, Morrison G, Golper TA, Pulliam J, Wolfson M, Singer I
Am J Kidney Dis. 1983 3 (3): 155-93

PMID: 6356890 · DOI:10.1016/s0272-6386(83)80060-2

The data base for rational guidelines to safe, efficacious drug prescribing in adults with renal insufficiency are presented in tabular form. Current medical literature was extensively surveyed to provide as much specific information as possible. When information is lacking, however, recommendations are based on pharmacokinetic variables in normal subjects. Nephrotoxicity, important adverse effects, and special considerations in renal patients are noted. Adjustments are suggested for hemodialysis and peritoneal dialysis when appropriate.

MeSH Terms (7)

Adult Drug Administration Schedule Drug Prescriptions Humans Kidney Failure, Chronic Kinetics Pharmaceutical Preparations

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