Prognostic implications of ventricular arrhythmias during 24 hour ambulatory monitoring in patients undergoing cardiac catheterization for coronary artery disease.

Califf RM, McKinnis RA, Burks J, Lee KL, Harrell FE, Behar VS, Pryor DB, Wagner GS, Rosati RA
Am J Cardiol. 1982 50 (1): 23-31

PMID: 6124117 · DOI:10.1016/0002-9149(82)90004-2

The prognostic importance of ventricular arrhythmias detected during 24 hour ambulatory monitoring was evaluated in 395 patients with and 260 patients without significant coronary artery disease. Ventricular arrhythmias were found to be strongly related to abnormal left ventricular function. A modification of the Lown grading system (ventricular arrhythmia score) was the most useful scheme for classifying ventricular arrhythmias according to prognostic importance. When only noninvasive characteristics were considered, the score contributed independent prognostic information, and the complexity of ventricular arrhythmias as measured by this score was inversely related to survival. However, when invasive measurements were included, the ventricular arrhythmia score did not contribute independent prognostic information. Furthermore, ejection fraction was more useful than the ventricular arrhythmia score in identifying patients at high risk of sudden death.

MeSH Terms (18)

Adrenergic beta-Antagonists Ambulatory Care Angina Pectoris Arrhythmias, Cardiac Cardiac Catheterization Cardiac Output Coronary Disease Death, Sudden Digoxin Electrocardiography Female Heart Ventricles Humans Male Middle Aged Myocardial Contraction Myocardial Infarction Prognosis

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