Platelet aggregates in peripheral and coronary-sinus blood in patients with spontaneous coronary-artery spasm.

Robertson RM, Robertson D, Friesinger GC, Timmons S, Hawiger J
Lancet. 1980 2 (8199): 829-31

PMID: 6107502 · DOI:10.1016/s0140-6736(80)90175-0

Five out of twenty patients with vasotonic angina had frequent spontaneous attacks with dramatic ST-segment alterations. These attacks were consistently associated with an increase in platelet aggregates in coronary-sinus blood but not arterial blood. This increase in platelet aggregates during coronary-artery spasm suggests a potential causal role for the platelet in this subset of patients with ischaemic heart-disease. However, the increase in platelet aggregates could be secondary to reduced coronary blood-flow.

MeSH Terms (16)

Adult Aged Angina Pectoris Angina Pectoris, Variant Chronic Disease Coronary Circulation Electrocardiography Female Humans Male Middle Aged Models, Biological Platelet Aggregation Platelet Function Tests Spasm Terminology as Topic

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