DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3.

Borza CM, Bolas G, Bock F, Zhang X, Akabogu FC, Zhang MZ, de Caestecker M, Yang M, Yang H, Lee E, Gewin L, Fogo AB, McDonald WH, Zent R, Pozzi A
JCI Insight. 2022 7 (3)

PMID: 34941574 · PMCID: PMC8855801 · DOI:10.1172/jci.insight.150887

MeSH Terms (18)

Acute Kidney Injury Animals Cell Line Cells, Cultured Discoidin Domain Receptor 1 Female Fibrosis Gene Expression Regulation Inflammation Kidney Tubules, Proximal Male Mice Mice, Knockout Phosphorylation Proto-Oncogene Proteins c-bcr RNA Signal Transduction STAT3 Transcription Factor

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