Stereospecific conversion of prostaglandin D2 to (5Z,13E)-(15S)-9 alpha-11 beta,15-trihydroxyprosta-5,13-dien-1-oic acid (9 alpha,11 beta-prostaglandin F2) and of prostaglandin H2 to prostaglandin F2 alpha by bovine lung prostaglandin F synthase.

Watanabe K, Iguchi Y, Iguchi S, Arai Y, Hayaishi O, Roberts LJ
Proc Natl Acad Sci U S A. 1986 83 (6): 1583-7

PMID: 3456602 · PMCID: PMC323127 · DOI:10.1073/pnas.83.6.1583

MeSH Terms (15)

Animals Binding Sites Cattle Dinoprost Hydroxyprostaglandin Dehydrogenases Lung Molecular Conformation Prostaglandin D2 Prostaglandin Endoperoxides Prostaglandin Endoperoxides, Synthetic Prostaglandin H2 Prostaglandins D Prostaglandins F Prostaglandins H Substrate Specificity

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