Apoptosis signal-regulating kinase 1 (ASK1) inhibition reduces endothelial cytokine production without improving permeability after toll-like receptor 4 (TLR4) challenge.

Miller MR, Koch SR, Choi H, Lamb FS, Stark RJ
Transl Res. 2021 235: 115-128

PMID: 33857660 · PMCID: PMC8328918 · DOI:10.1016/j.trsl.2021.04.001

MeSH Terms (11)

Cells, Cultured Cytokines Endothelial Cells Humans JNK Mitogen-Activated Protein Kinases MAP Kinase Kinase Kinase 5 MAP Kinase Signaling System Nitric Oxide Synthase Type III p38 Mitogen-Activated Protein Kinases Permeability Toll-Like Receptor 4

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