A Genetic Mouse Model Recapitulates Immune Checkpoint Inhibitor-Associated Myocarditis and Supports a Mechanism-Based Therapeutic Intervention.

Wei SC, Meijers WC, Axelrod ML, Anang NAS, Screever EM, Wescott EC, Johnson DB, Whitley E, Lehmann L, Courand PY, Mancuso JJ, Himmel LE, Lebrun-Vignes B, Wleklinski MJ, Knollmann BC, Srinivasan J, Li Y, Atolagbe OT, Rao X, Zhao Y, Wang J, Ehrlich LIR, Sharma P, Salem JE, Balko JM, Moslehi JJ, Allison JP
Cancer Discov. 2021 11 (3): 614-625

PMID: 33257470 · PMCID: PMC8041233 · DOI:10.1158/2159-8290.CD-20-0856

MeSH Terms (13)

Animals Biomarkers, Tumor Cardiotoxicity Disease Management Disease Models, Animal Disease Susceptibility Electrocardiography Humans Immune Checkpoint Inhibitors Mice Molecular Targeted Therapy Myocarditis Neoplasms

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