Heart slice culture system reliably demonstrates clinical drug-related cardiotoxicity.

Miller JM, Meki MH, Ou Q, George SA, Gams A, Abouleisa RRE, Tang XL, Ahern BM, Giridharan GA, El-Baz A, Hill BG, Satin J, Conklin DJ, Moslehi J, Bolli R, Ribeiro AJS, Efimov IR, Mohamed TMA
Toxicol Appl Pharmacol. 2020 406: 115213

PMID: 32877659 · PMCID: PMC7554180 · DOI:10.1016/j.taap.2020.115213

MeSH Terms (18)

Adult Aged Animals Antineoplastic Agents Apoptosis Cardiotoxicity Cardiotoxins Doxorubicin Female Heart Humans Induced Pluripotent Stem Cells Male Middle Aged Models, Biological Swine Tissue Culture Techniques Trastuzumab

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