Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation.

Banerjee A, Herring CA, Chen B, Kim H, Simmons AJ, Southard-Smith AN, Allaman MM, White JR, Macedonia MC, Mckinley ET, Ramirez-Solano MA, Scoville EA, Liu Q, Wilson KT, Coffey RJ, Washington MK, Goettel JA, Lau KS
Gastroenterology. 2020 159 (6): 2101-2115.e5

PMID: 32828819 · PMCID: PMC7725941 · DOI:10.1053/j.gastro.2020.08.029

MeSH Terms (21)

Animals Basic Helix-Loop-Helix Transcription Factors Chemoreceptor Cells Crohn Disease Disease Models, Animal DNA, Bacterial Feces Female Gastrointestinal Microbiome Humans Ileitis Ileum Intestinal Mucosa Male Mice Mice, Knockout Protective Factors RNA, Ribosomal, 16S RNA-Seq Single-Cell Analysis Succinic Acid

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