CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation.

Beckermann KE, Hongo R, Ye X, Young K, Carbonell K, Healey DCC, Siska PJ, Barone S, Roe CE, Smith CC, Vincent BG, Mason FM, Irish JM, Rathmell WK, Rathmell JC
JCI Insight. 2020 5 (16)

PMID: 32814710 · PMCID: PMC7455120 · DOI:10.1172/jci.insight.138729

MeSH Terms (14)

Carcinoma, Renal Cell CD8-Positive T-Lymphocytes CD28 Antigens Gene Expression Regulation Glucose Glycolysis Humans Interleukin-7 Kidney Neoplasms Lymphocytes, Tumor-Infiltrating Mitochondria Nephritis Single-Cell Analysis Tumor Microenvironment

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