Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction.

Lim SP, Costantini B, Mian SA, Perez Abellan P, Gandhi S, Martinez Llordella M, Lozano JJ, Antunes Dos Reis R, Povoleri GAM, Mourikis TP, Abarrategi A, Ariza-McNaughton L, Heck S, Irish JM, Lombardi G, Marsh JCW, Bonnet D, Kordasti S, Mufti GJ
Blood. 2020 136 (7): 885-897

PMID: 32294156 · PMCID: PMC7532000 · DOI:10.1182/blood.2019001347

MeSH Terms (16)

Anemia, Aplastic Animals Apoptosis Cells, Cultured Fas Ligand Protein Female Humans Immune System Diseases Immune Tolerance Interleukin-2 Male Mice Mice, Inbred NOD Mice, SCID Mice, Transgenic T-Lymphocytes, Regulatory

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