Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease.

Mosley JD, Gupta DK, Tan J, Yao J, Wells QS, Shaffer CM, Kundu S, Robinson-Cohen C, Psaty BM, Rich SS, Post WS, Guo X, Rotter JI, Roden DM, Gerszten RE, Wang TJ
JAMA. 2020 323 (7): 627-635

PMID: 32068817 · PMCID: PMC7042849 · DOI:10.1001/jama.2019.21782

MeSH Terms (21)

Aged Cohort Studies Coronary Disease Female Genetic Predisposition to Disease Genome-Wide Association Study Genotype Humans Incidence Male Middle Aged Multifactorial Inheritance Myocardial Infarction Odds Ratio Phenotype Polymorphism, Single Nucleotide Predictive Value of Tests Proportional Hazards Models Retrospective Studies Risk Risk Assessment

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