The present study tests the hypothesis that early wound healing effects blood flow after experimental microarteriorrhaphy. Hemodynamic variables were measured in the rat femoral artery prior to and 3 weeks after both interrupted and continuous microarteriorrhaphy techniques. The hemodynamic variables (blood velocities, lumen geometry, and calculated blood flow) were measured by 20-MHz pulsed ultrasonic Doppler velocity meter (PUDVM) methods. The control values (N = 22) and the 3 weeks postoperative values, for both the interrupted (N = 11) and continuous groups (N = 11), were not statistically different (P greater than .01). The average calculated blood flows were as follows: control group 10.85 +/- 1.45 cc/min, interrupted group 12.01 +/- .92 cc/min, and continuous group 8.50 +/- 1.45 cc/min. Three weeks of wound healing after microarteriorrhaphy did not significantly change blood flow variables compared to preoperative values.