Systemic delivery of a Gli inhibitor via polymeric nanocarriers inhibits tumor-induced bone disease.

Vanderburgh JP, Kwakwa KA, Werfel TA, Merkel AR, Gupta MK, Johnson RW, Guelcher SA, Duvall CL, Rhoades JA
J Control Release. 2019 311-312: 257-272

PMID: 31494183 · PMCID: PMC7007697 · DOI:10.1016/j.jconrel.2019.08.038

MeSH Terms (23)

Animals Antineoplastic Agents Apoptosis Bone Neoplasms Cell Line, Tumor Cell Proliferation Cell Survival Drug Carriers Drug Liberation Female Gene Expression Regulation, Neoplastic Humans Mammary Neoplasms, Animal Mesenchymal Stem Cells Mice, Inbred C57BL Mice, Knockout Mice, Nude Nanoparticles Osteogenesis Polymers Pyridines Thiophenes Zinc Finger Protein Gli2

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