Sign Inversion in Photopharmacology: Incorporation of Cyclic Azobenzenes in Photoswitchable Potassium Channel Blockers and Openers.

Trads JB, Hüll K, Matsuura BS, Laprell L, Fehrentz T, Görldt N, Kozek KA, Weaver CD, Klöcker N, Barber DM, Trauner D
Angew Chem Int Ed Engl. 2019 58 (43): 15421-15428

PMID: 31441199 · DOI:10.1002/anie.201905790

MeSH Terms (13)

Action Potentials Azo Compounds Cyclization Drug Design G Protein-Coupled Inwardly-Rectifying Potassium Channels HEK293 Cells Humans Isomerism Lidocaine Light Patch-Clamp Techniques Potassium Channel Blockers Thermodynamics

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