Dynamics of drug response informs rational combination regimens.

Paudel BB, Quaranta V
Sci Signal. 2019 12 (595)

PMID: 31431544 · DOI:10.1126/scisignal.aax9742

Metabolic plasticity in cancer has been linked to the development of drug-tolerant populations. In this issue of , Goldman integrate metabolic plasticity with phenotypic state transitions to examine how this reprogramming can be therapeutically exploited.

Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

MeSH Terms (5)

Adaptation, Physiological Drug Tolerance Humans Neoplasms Signal Transduction

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