The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA binding protein Mcm10.

Paulson CN, John K, Baxley RM, Kurniawan F, Orellana K, Francis R, Sobeck A, Eichman BF, Chazin WJ, Aihara H, Georg GI, Hawkinson JE, Bielinsky AK
Open Biol. 2019 9 (8): 190117

PMID: 31409229 · PMCID: PMC6731595 · DOI:10.1098/rsob.190117

MeSH Terms (15)

Animals Cell Survival DNA-Binding Proteins DNA Replication Drug Discovery Enzyme Inhibitors Gene Expression High-Throughput Nucleotide Sequencing Humans Kinetics Minichromosome Maintenance Proteins Molecular Structure Protein Binding Suramin Xenopus

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