A recommended and verified procedure for in situ tryptic digestion of formalin-fixed paraffin-embedded tissues for analysis by matrix-assisted laser desorption/ionization imaging mass spectrometry.

Judd AM, Gutierrez DB, Moore JL, Patterson NH, Yang J, Romer CE, Norris JL, Caprioli RM
J Mass Spectrom. 2019 54 (8): 716-727

PMID: 31254303 · PMCID: PMC6711785 · DOI:10.1002/jms.4384

MeSH Terms (10)

Formaldehyde Humans Paraffin Embedding Proteins Proteolysis Specimen Handling Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Tissue Array Analysis Tissue Fixation Trypsin

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