Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether.

Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P
Elife. 2019 8

PMID: 31149896 · PMCID: PMC6588346 · DOI:10.7554/eLife.46595

MeSH Terms (13)

Activating Transcription Factor 6 ATP-Binding Cassette Transporters CRISPR-Cas Systems Endoplasmic Reticulum HEK293 Cells Hep G2 Cells Humans Organelles Peroxisomes Phenotype Protein Binding Small Molecule Libraries Unfolded Protein Response

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