Mitochondrially targeted cytochrome P450 2D6 is involved in monomethylamine-induced neuronal damage in mouse models.

Chattopadhyay M, Chowdhury AR, Feng T, Assenmacher CA, Radaelli E, Guengerich FP, Avadhani NG
J Biol Chem. 2019 294 (26): 10336-10348

PMID: 31113867 · PMCID: PMC6664168 · DOI:10.1074/jbc.RA119.008848

MeSH Terms (16)

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Animals Cytochrome P-450 CYP2D6 Disease Models, Animal Humans Male Methylamines Mice Mice, Inbred C57BL Mice, Knockout Mitochondria Neuroblastoma Neurons Neurotoxins Parkinson Disease Tumor Cells, Cultured

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