Conformational selection dominates binding of steroids to human cytochrome P450 17A1.

Guengerich FP, Wilkey CJ, Glass SM, Reddish MJ
J Biol Chem. 2019 294 (26): 10028-10041

PMID: 31072872 · PMCID: PMC6664176 · DOI:10.1074/jbc.RA119.008860

MeSH Terms (8)

17-alpha-Hydroxypregnenolone 17-alpha-Hydroxyprogesterone Androstenes Humans Kinetics Protein Conformation Steroid 17-alpha-Hydroxylase Substrate Specificity

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