Hypoxia-inducible factors in CD4 T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity.

Cho SH, Raybuck AL, Blagih J, Kemboi E, Haase VH, Jones RG, Boothby MR
Proc Natl Acad Sci U S A. 2019 116 (18): 8975-8984

PMID: 30988188 · PMCID: PMC6500120 · DOI:10.1073/pnas.1811702116

MeSH Terms (20)

Animals Antibody Formation B-Lymphocytes Basic Helix-Loop-Helix Transcription Factors CD4-Positive T-Lymphocytes Cell Hypoxia Cytokines Germinal Center Humans Hypoxia Hypoxia-Inducible Factor 1, alpha Subunit Immunity, Humoral Immunization Lymphocyte Activation Mice Mice, Inbred C57BL Mice, Transgenic Receptors, CXCR5 Sheep T-Lymphocytes, Helper-Inducer

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