Genome-Wide Association and Functional Studies Reveal Novel Pharmacological Mechanisms for Allopurinol.

Brackman DJ, Yee SW, Enogieru OJ, Shaffer C, Ranatunga D, Denny JC, Wei WQ, Kamatani Y, Kubo M, Roden DM, Jorgenson E, Giacomini KM
Clin Pharmacol Ther. 2019 106 (3): 623-631

PMID: 30924126 · PMCID: PMC6941886 · DOI:10.1002/cpt.1439

MeSH Terms (16)

Aged Aged, 80 and over Allopurinol ATP Binding Cassette Transporter, Subfamily G, Member 2 Cytokines Ethnic Groups Female Genome-Wide Association Study Glucose Transport Proteins, Facilitative Humans Male Middle Aged Neoplasm Proteins Oxypurinol Prognosis Uric Acid

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