Systemic bile acids induce insulin resistance in a TGR5-independent manner.

Syring KE, Cyphert TJ, Beck TC, Flynn CR, Mignemi NA, McGuinness OP
Am J Physiol Endocrinol Metab. 2019 316 (5): E782-E793

PMID: 30779633 · PMCID: PMC6732652 · DOI:10.1152/ajpendo.00362.2018

MeSH Terms (19)

Animals Bile Acids and Salts Cholagogues and Choleretics Cholic Acids Deoxycholic Acid Gene Expression Profiling Gluconeogenesis Glucose Clamp Technique Hepatocytes Hep G2 Cells Humans Insulin Resistance Liver Mice Mice, Knockout Obesity Primary Cell Culture Receptors, G-Protein-Coupled Taurocholic Acid

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