Glutamine-451 Confers Sensitivity to Oxidative Inhibition and Heme-Thiolate Sulfenylation of Cytochrome P450 4B1.

Albertolle ME, Song HD, Wilkey CJ, Segrest JP, Guengerich FP
Chem Res Toxicol. 2019 32 (3): 484-492

PMID: 30701961 · PMCID: PMC7279892 · DOI:10.1021/acs.chemrestox.8b00353

MeSH Terms (10)

Animals Aryl Hydrocarbon Hydroxylases Glutamine Heme Molecular Dynamics Simulation Mutagenesis, Site-Directed Oxidation-Reduction Rabbits Sulfenic Acids Sulfhydryl Compounds

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