Thrombotic microangiopathy as a cause of cardiovascular toxicity from the BCR-ABL1 tyrosine kinase inhibitor ponatinib.

Latifi Y, Moccetti F, Wu M, Xie A, Packwood W, Qi Y, Ozawa K, Shentu W, Brown E, Shirai T, McCarty OJ, Ruggeri Z, Moslehi J, Chen J, Druker BJ, López JA, Lindner JR
Blood. 2019 133 (14): 1597-1606

PMID: 30692122 · PMCID: PMC6450432 · DOI:10.1182/blood-2018-10-881557

MeSH Terms (16)

Animals Aorta Cardiovascular Diseases Endothelium Fusion Proteins, bcr-abl Humans Imidazoles Ischemia Mice Mice, Knockout Platelet Adhesiveness Protein Kinase Inhibitors Pyridazines Thrombotic Microangiopathies Ventricular Dysfunction von Willebrand Factor

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