The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains.

Starbird CA, Perry NA, Chen Q, Berndt S, Yamakawa I, Loukachevitch LV, Limbrick EM, Bachmann BO, Iverson TM, McCulloch KM
Biochemistry. 2018 57 (50): 6827-6837

PMID: 30525509 · PMCID: PMC7231510 · DOI:10.1021/acs.biochem.8b00836

MeSH Terms (15)

Amino Acid Sequence Aminoglycosides Bacterial Proteins Biosynthetic Pathways Catalytic Domain Conserved Sequence Crystallography, X-Ray Gene Fusion Genes, Bacterial Methyltransferases Micromonospora Models, Molecular Oxygenases Protein Interaction Domains and Motifs Sequence Homology, Amino Acid

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