Binding of a physiological substrate causes large-scale conformational reorganization in cytochrome P450 51.

Hargrove TY, Wawrzak Z, Fisher PM, Child SA, Nes WD, Guengerich FP, Waterman MR, Lepesheva GI
J Biol Chem. 2018 293 (50): 19344-19353

PMID: 30327430 · PMCID: PMC6302162 · DOI:10.1074/jbc.RA118.005850

MeSH Terms (9)

Biocatalysis Electron Transport Enzyme Stability Heme Models, Molecular Protein Binding Protein Conformation Sterol 14-Demethylase Trypanosoma cruzi

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