Structure-function analyses of the ion channel TRPC3 reveal that its cytoplasmic domain allosterically modulates channel gating.

Sierra-Valdez F, Azumaya CM, Romero LO, Nakagawa T, Cordero-Morales JF
J Biol Chem. 2018 293 (41): 16102-16114

PMID: 30139744 · PMCID: PMC6187627 · DOI:10.1074/jbc.RA118.005066

MeSH Terms (9)

Allosteric Regulation Ankyrin Repeat HEK293 Cells Humans Ion Channel Gating Mutation Protein Conformation, alpha-Helical Protein Domains TRPC Cation Channels

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