Discovery of Tricyclic Triazolo- and Imidazopyridine Lactams as M Positive Allosteric Modulators.

Engers JL, Bender AM, Kalbfleisch JJ, Cho HP, Lingenfelter KS, Luscombe VB, Han C, Melancon BJ, Blobaum AL, Dickerson JW, Rook JM, Niswender CM, Emmitte KA, Conn PJ, Lindsley CW
ACS Chem Neurosci. 2019 10 (3): 1035-1042

PMID: 30086237 · PMCID: PMC6456254 · DOI:10.1021/acschemneuro.8b00311

MeSH Terms (11)

Allosteric Regulation Animals Drug Discovery Humans Imidazoles Lactams Mice Muscarinic Agonists Pyridines Rats Receptor, Muscarinic M1

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