Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes.

Navarro G, Allard C, Morford JJ, Xu W, Liu S, Molinas AJ, Butcher SM, Fine NH, Blandino-Rosano M, Sure VN, Yu S, Zhang R, Münzberg H, Jacobson DA, Katakam PV, Hodson DJ, Bernal-Mizrachi E, Zsombok A, Mauvais-Jarvis F
JCI Insight. 2018 3 (12)

PMID: 29925687 · PMCID: PMC6124401 · DOI:10.1172/jci.insight.98607

MeSH Terms (19)

Androgens Animals Diabetes Mellitus, Type 2 Diet, Western Dihydrotestosterone Female Glucose Humans Hyperinsulinism Hypothalamus Insulin-Secreting Cells Insulin Resistance Mice Mice, Inbred C57BL Mice, Knockout Mitochondria Neurons Receptors, Androgen Streptozocin

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