Discovery, Characterization, and Effects on Renal Fluid and Electrolyte Excretion of the Kir4.1 Potassium Channel Pore Blocker, VU0134992.

Kharade SV, Kurata H, Bender AM, Blobaum AL, Figueroa EE, Duran A, Kramer M, Days E, Vinson P, Flores D, Satlin LM, Meiler J, Weaver CD, Lindsley CW, Hopkins CR, Denton JS
Mol Pharmacol. 2018 94 (2): 926-937

PMID: 29895592 · PMCID: PMC6041953 · DOI:10.1124/mol.118.112359

MeSH Terms (15)

Animals Binding Sites Diuretics Electrolytes HEK293 Cells Humans Male Models, Molecular Molecular Docking Simulation Molecular Structure Mutagenesis, Site-Directed Potassium Channels, Inwardly Rectifying Rats Small Molecule Libraries Substrate Specificity

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