Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide.

Loperena R, Van Beusecum JP, Itani HA, Engel N, Laroumanie F, Xiao L, Elijovich F, Laffer CL, Gnecco JS, Noonan J, Maffia P, Jasiewicz-Honkisz B, Czesnikiewicz-Guzik M, Mikolajczyk T, Sliwa T, Dikalov S, Weyand CM, Guzik TJ, Harrison DG
Cardiovasc Res. 2018 114 (11): 1547-1563

PMID: 29800237 · PMCID: PMC6106108 · DOI:10.1093/cvr/cvy112

MeSH Terms (25)

Aged Angiotensin II Animals Blood Pressure Case-Control Studies Cell Communication Cell Differentiation Cells, Cultured Coculture Techniques Disease Models, Animal Endothelial Cells Female Humans Hydrogen Peroxide Hypertension Interleukin-6 Male Mechanotransduction, Cellular Mice, Inbred C57BL Middle Aged Monocytes Nitric Oxide Phenotype STAT3 Transcription Factor Stress, Mechanical

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