Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma.

Chiang YC, Park IY, Terzo EA, Tripathi DN, Mason FM, Fahey CC, Karki M, Shuster CB, Sohn BH, Chowdhury P, Powell RT, Ohi R, Tsai YS, de Cubas AA, Khan A, Davis IJ, Strahl BD, Parker JS, Dere R, Walker CL, Rathmell WK
Cancer Res. 2018 78 (12): 3135-3146

PMID: 29724720 · PMCID: PMC6004258 · DOI:10.1158/0008-5472.CAN-17-3460

MeSH Terms (19)

Animals Carcinogenesis Carcinoma, Renal Cell Cell Line, Tumor Chromosomes, Human, Pair 3 Fibroblasts Gene Knockdown Techniques Genomic Instability Haploinsufficiency Histone-Lysine N-Methyltransferase Histones Humans Kidney Neoplasms Kidney Tubules, Proximal Lysine Methylation Mice Micronuclei, Chromosome-Defective Microtubules

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