Nuclear PTEN enhances the maturation of a microRNA regulon to limit MyD88-dependent susceptibility to sepsis.

Sisti F, Wang S, Brandt SL, Glosson-Byers N, Mayo LD, Son YM, Sturgeon S, Filgueiras L, Jancar S, Wong H, Dela Cruz CS, Andrews N, Alves-Filho JC, Cunha FQ, Serezani CH
Sci Signal. 2018 11 (528)

PMID: 29717063 · PMCID: PMC8147521 · DOI:10.1126/scisignal.aai9085

MeSH Terms (17)

Animals Cell Nucleus Female Gene Expression Profiling Humans Inflammation Macrophages Male Mice, Inbred C57BL Mice, Knockout MicroRNAs Myeloid Differentiation Factor 88 Peptides PTEN Phosphohydrolase Regulon RNA Interference Sepsis

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