Pathogenic Germline Variants in 10,389 Adult Cancers.

Huang KL, Mashl RJ, Wu Y, Ritter DI, Wang J, Oh C, Paczkowska M, Reynolds S, Wyczalkowski MA, Oak N, Scott AD, Krassowski M, Cherniack AD, Houlahan KE, Jayasinghe R, Wang LB, Zhou DC, Liu D, Cao S, Kim YW, Koire A, McMichael JF, Hucthagowder V, Kim TB, Hahn A, Wang C, McLellan MD, Al-Mulla F, Johnson KJ, Cancer Genome Atlas Research Network, Lichtarge O, Boutros PC, Raphael B, Lazar AJ, Zhang W, Wendl MC, Govindan R, Jain S, Wheeler D, Kulkarni S, Dipersio JF, Reimand J, Meric-Bernstam F, Chen K, Shmulevich I, Plon SE, Chen F, Ding L
Cell. 2018 173 (2): 355-370.e14

PMID: 29625052 · PMCID: PMC5949147 · DOI:10.1016/j.cell.2018.03.039

MeSH Terms (16)

Databases, Genetic DNA Copy Number Variations Gene Deletion Gene Frequency Genetic Predisposition to Disease Genotype Germ-Line Mutation Germ Cells Humans Loss of Heterozygosity Mutation, Missense Neoplasms Polymorphism, Single Nucleotide Proto-Oncogene Proteins c-met Proto-Oncogene Proteins c-ret Tumor Suppressor Proteins

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