The unassembled flavoprotein subunits of human and bacterial complex II have impaired catalytic activity and generate only minor amounts of ROS.

Maklashina E, Rajagukguk S, Iverson TM, Cecchini G
J Biol Chem. 2018 293 (20): 7754-7765

PMID: 29610278 · PMCID: PMC5961047 · DOI:10.1074/jbc.RA118.001977

MeSH Terms (12)

Bacterial Proteins Catalysis Crystallography, X-Ray Electron Transport Complex II Escherichia coli Flavoproteins Humans Models, Molecular Oxidation-Reduction Protein Conformation Protein Subunits Reactive Oxygen Species

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