Gallium Maltolate Disrupts Tumor Iron Metabolism and Retards the Growth of Glioblastoma by Inhibiting Mitochondrial Function and Ribonucleotide Reductase.

Chitambar CR, Al-Gizawiy MM, Alhajala HS, Pechman KR, Wereley JP, Wujek R, Clark PA, Kuo JS, Antholine WE, Schmainda KM
Mol Cancer Ther. 2018 17 (6): 1240-1250

PMID: 29592883 · PMCID: PMC5984712 · DOI:10.1158/1535-7163.MCT-17-1009

MeSH Terms (18)

Animals Antineoplastic Agents Brain Cell Line, Tumor Disease Models, Animal Glioblastoma Heterografts Humans Immunohistochemistry Iron Male Mitochondria Organometallic Compounds Pyrones Rats Receptors, Transferrin Ribonucleoside Diphosphate Reductase Ribonucleotide Reductases

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