Neuronal Fat and Dendrite Morphogenesis: The Goldilocks Effect.

Sundararajan L, Miller DM
Trends Neurosci. 2018 41 (5): 250-252

PMID: 29548516 · PMCID: PMC5924613 · DOI:10.1016/j.tins.2018.02.011

Two recent studies by Meltzer et al. and Ziegler et al. use Drosophila larvae to demonstrate that cell-autonomous regulation of lipid biosynthesis defines the complexity and function of highly branched nociceptive neurons. Their findings show that lipid biosynthesis in the neuron is fine-tuned for optimal dendrite morphology and sensitivity.

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MeSH Terms (7)

Animals Dendrites Drosophila Drosophila Proteins Larva Morphogenesis Neurogenesis

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