Evaluation of the novel TSPO radiotracer 2-(7-butyl-2-(4-(2-([F]fluoroethoxy)phenyl)-5-methylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide in a preclinical model of neuroinflammation.

Tang D, Fujinaga M, Hatori A, Zhang Y, Yamasaki T, Xie L, Mori W, Kumata K, Liu J, Manning HC, Huang G, Zhang MR
Eur J Med Chem. 2018 150: 1-8

PMID: 29505933 · DOI:10.1016/j.ejmech.2018.02.076

MeSH Terms (21)

Animals Disease Models, Animal Dose-Response Relationship, Drug Fluorine Radioisotopes Humans Inflammation Ischemia Male Mice Molecular Probes Molecular Structure Positron-Emission Tomography Pyrazoles Pyrimidines Radioactive Tracers Radiopharmaceuticals Rats Rats, Sprague-Dawley Receptors, GABA Structure-Activity Relationship Tissue Distribution

Connections (1)

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