Von Hippel-Lindau mutations disrupt vascular patterning and maturation via Notch.

Arreola A, Payne LB, Julian MH, de Cubas AA, Daniels AB, Taylor S, Zhao H, Darden J, Bautch VL, Rathmell WK, Chappell JC
JCI Insight. 2018 3 (4)

PMID: 29467323 · PMCID: PMC5916240 · DOI:10.1172/jci.insight.92193

MeSH Terms (19)

Animals Diamines Disease Models, Animal Endothelial Cells Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Hemangioblastoma Humans Male Mice Mice, Transgenic Microvessels Mutation Receptors, Notch Retinal Artery Thiazoles von Hippel-Lindau Disease Von Hippel-Lindau Tumor Suppressor Protein

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