Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody.

Kwon YD, Chuang GY, Zhang B, Bailer RT, Doria-Rose NA, Gindin TS, Lin B, Louder MK, McKee K, O'Dell S, Pegu A, Schmidt SD, Asokan M, Chen X, Choe M, Georgiev IS, Jin V, Pancera M, Rawi R, Wang K, Chaudhuri R, Kueltzo LA, Manceva SD, Todd JP, Scorpio DG, Kim M, Reinherz EL, Wagh K, Korber BM, Connors M, Shapiro L, Mascola JR, Kwong PD
Cell Rep. 2018 22 (7): 1798-1809

PMID: 29444432 · PMCID: PMC5889116 · DOI:10.1016/j.celrep.2018.01.023

MeSH Terms (10)

Antibodies, Neutralizing Cell Membrane Half-Life HIV-1 HIV Antibodies HIV Envelope Protein gp41 Humans Neutralization Tests Polysaccharides Protein Binding

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