Dual cyclooxygenase-fatty acid amide hydrolase inhibitor exploits novel binding interactions in the cyclooxygenase active site.

Goodman MC, Xu S, Rouzer CA, Banerjee S, Ghebreselasie K, Migliore M, Piomelli D, Marnett LJ
J Biol Chem. 2018 293 (9): 3028-3038

PMID: 29326169 · PMCID: PMC5836124 · DOI:10.1074/jbc.M117.802058

MeSH Terms (10)

Amidohydrolases Catalytic Domain Cyclooxygenase Inhibitors Isoenzymes Phenylcarbamates Phenylpropionates Prostaglandin-Endoperoxide Synthases Protein Binding Stereoisomerism Substrate Specificity

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