The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding.

King LB, Fusco ML, Flyak AI, Ilinykh PA, Huang K, Gunn B, Kirchdoerfer RN, Hastie KM, Sangha AK, Meiler J, Alter G, Bukreyev A, Crowe JE, Saphire EO
Cell Host Microbe. 2018 23 (1): 101-109.e4

PMID: 29324225 · PMCID: PMC5772738 · DOI:10.1016/j.chom.2017.12.003

MeSH Terms (22)

Agrobacterium tumefaciens Animals Antibodies, Monoclonal Antibodies, Neutralizing Antibodies, Viral Binding Sites Carrier Proteins Cell Line Chlorocebus aethiops Crystallography, X-Ray Drosophila melanogaster Humans Intracellular Signaling Peptides and Proteins Marburgvirus Membrane Glycoproteins Niemann-Pick C1 Protein Receptors, Virus Tobacco Vero Cells Viral Envelope Proteins Viral Fusion Proteins Virus Attachment

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